I had a great time giving an unusual talk at the Quantified Self meetup in SF last week. Several people asked me to post slides online. There were also a few questions we didn’t have time to address to which this is a partial answer.
Self-Experimentation without a Written Record
Tracking my lifestyle changes and related symptoms on an ongoing basis has proved to be challenging. The severity of my symptoms have never been such that I’ve made detailed note-taking a priority. Instead, I slowly evolved a mental methodology for keeping track of my experiences by focusing on one hypothesis at a time and slowly accumulating what I consider to be informative observations and conclusions.
In practice, I mentally maintain two mental ‘records’:
- Working Model: a collection of beliefs about the phenomenology of my body and environment. Often I’ll have multiple competing hypotheses about what is going on. My experiments are performed to test or compare hypotheses.
- Compiled Experience: my mental summary of past experience, effectively a list of if-then casual observations I’ve taken away from my experiment. I’m never afraid to go back and question one if future evidence is contradictory.
- Educate yourself Augment your working model by talking to professionals, fellow sufferers, sharing stories, reading blogs, reading the medical literature, etc.
- Pick one Hypothesis Given your current experience, pick a hypothesis to test that best fits the evidence you’ve collected and the mental model you have of what is going on.
- Focus What do you need to measure? Pick no more than 2-3 things. I often use a 3 point scale for fatigue, mood, and skin symptoms. I also look out for big events like onset of blurry vision, bad back pain or disturbed sleep.
- Confounders What else could cause the things you are tracking to vary? You’ll have to watch those two. Just focus on the big ones. For example with fatigue and mood, the amount of sleep and exercise is very important (and I do use a Zeo now and again now for this). When I don’t sleep, I expect scores to decline. When I exercise I expect them to improve.
- Experiment Try to keep your habits the same, change one thing implied by your theory and mentally track whether there is a change. If you have a change in one of the big confounding variables, then I delay an observation until the next cycle or make a mental adjustment.
- Repeat Do the experiment over and over until you are pretty sure you have or have not seen a consistent effect. Pay special attention to the confounders.
- Update your Experience I maintain a list of foods that seem benign or problematic, a list of symptoms that co-vary together, I’m slowly understand what problematic components different foods have (fructose, histamine, gluten, etc), how to think about my current state of being, etc.
- Return to Step 1 Education is critical because you are making judgements about what will or won’t be harmful and it is finding stories of people with similar conditions to you that helps you make sense of your compiled experience and find breakthroughs in your working model.
This methodology only works well when several conditions hold. You must have a relatively short window between treatment and effect, the treatment must not have significant short-term effects on your overall condition, etc. This is typically true for sleep problems, dietary sensitivities, supplements, mild skin and mood conditions, etc. IF you aren’t going to be aggressive about measuring or tracking, you’ll need patience instead. This model only leads to discovery after many repeated trials over months or even years. Repeated experiments are the only way to start peering through the complexity of your body and the limitations of your mind’s ability to correctly recall past events.
There are a few key things to keep an eye out for that can significantly improve the experimental process.
- Find a Baseline Can you get to a healthy state? Can you find a stable condition (aka “normal”). If so, you can use this as a basis for experiments. Some methods relevant to discovering a baseline includes:
a. Elimination diets / fasting. Removing all possible dietary triggers can be helpful.
b. Symptom suppressing drugs (separate condition from other life factors)
c. Regularity of schedule. These experiments are easier to perform when your daily routine is extremely consistent.
- Co-varying symptoms Identifying which of your minor ailments or symptoms all vary together is highly informative
a. Clustering symptoms may help identify multiple conditions
b. Symptoms that normally cluster may sometimes not cluster which tells you something about your condition or possible confounders.
QS Talk Video
QS Talk Slides